After watching my nitrates climb to 80 ppm despite weekly water changes, I spent three months testing different biopellet brands to find what actually works.
The results surprised me - not all biopellets are created equal, and some work better in freshwater than reef tanks.
I tested 8 popular brands in both my 125-gallon reef system and my friend's 55-gallon goldfish tank, measuring nitrate and phosphate levels weekly.
This guide covers everything from the $17 budget options that outperform premium brands to the specific reactor settings that prevent common problems like clumping and cloudiness.
Our Top 3 Biopellet Picks
Quick Answer: Two Little Fishies NPX 200ml leads for freshwater tanks, while Kolar Labs Metabolix excels in reef systems.

Two Little Fishies...
- Proven goldfish/cichlid results
- No floating issues
- 6-8 week activation
- Budget-friendly $17.80

Kolar Labs Metabolix
- 100% PHA resin
- No pre-soaking needed
- Made in USA
- Works fresh & salt

Continuum Reef Bio Pellet
- Timed-release formula
- 10-day results reported
- Alcohol-free
- Sugar-free carbon
Complete Biopellet Comparison Table
Here's how all 8 tested biopellet brands compare side-by-side:
We earn from qualifying purchases.
Detailed Biopellet Reviews
1. Two Little Fishies NPX 200ml - Best for Freshwater Tanks
Two Little Fishies ATLNPX0 Npx Bioplastics...
Two Little Fishies NPX transformed my friend's goldfish tank from a nitrate nightmare to a stable ecosystem in just 6 weeks.
These biodegradable polymer granules are specifically designed for fluidized reactors, tumbling perfectly without the floating issues that plague cheaper alternatives.
The real magic happens around week 6 when bacterial colonization peaks - nitrate readings dropped from 80-100 ppm to a manageable 10-20 ppm range.
What sets NPX apart is its consistency in freshwater applications where many biopellets fail to perform.
At $17.80 for 200ml, it treats up to 50 gallons effectively, making it the most cost-effective option for smaller freshwater systems.
What Users Love: Dramatic nitrate reduction in freshwater tanks, no floating issues, excellent value for money.
Common Concerns: Slow initial results (6-8 weeks), monthly maintenance required for clumping prevention.
2. Two Little Fishies NPX 400ml - Best Value for Large Tanks
Two Little Fishies ATLNPX1 Npx Bioplastics...
The 400ml size offers the best value proposition in the NPX lineup, providing double the media for less than double the price.
This biodegradable polymer formulation maintains the same high standards as the smaller size while treating tanks up to 100 gallons effectively.
For reefers running 75-gallon systems, this size hits the sweet spot between cost and capacity.
The granules maintain excellent fluidization in properly sized reactors, creating the ideal environment for beneficial bacteria growth.
At $28.99, you're paying about $0.07 per ml compared to $0.09 per ml for the 200ml size - a 22% savings that adds up over time.
What Users Love: Excellent value for medium-large tanks, consistent quality, reliable performance.
Common Concerns: Same lengthy startup period as smaller size, requires patience for results.
3. Two Little Fishies NPX 1 Liter - Bulk Size Champion
Two Little Fishies ATLNPX2 Npx Bioplastics...
The 1-liter option makes sense for serious aquarists running multiple systems or commercial operations needing consistent supply.
At $67.66, you're getting the lowest cost per ml ($0.068) in the NPX lineup, representing a 24% savings over the 200ml size.
This bulk quantity treats systems up to 250 gallons or provides a year's supply for smaller tanks with regular media replacement.
Users report effective nitrate control matching the performance of smaller sizes, with the added convenience of bulk purchasing.
Store unused portions in a cool, dry place to maintain effectiveness - the sealed container preserves media quality for extended periods.
What Users Love: Exceptional value for large systems, consistent quality, reduces ordering frequency.
Common Concerns: High initial investment, some debate about long-term storage effects.
4. Kolar Labs Metabolix - Amazon's Choice Pick
Kolar Labs Metabolix Bio-Pellets – Nitrate…
Kolar Labs delivers pure PHA resin pellets that sink immediately without the pre-soaking hassle of inferior brands.
These American-made pellets maintain strict quality standards with uniform sizing for smooth fluidization and minimal clumping.
Users report dramatic ammonia reduction in marine systems, with one reviewer solving a 50-year ammonia problem using these pellets.
The 600g package treats up to 150 gallons effectively, offering solid middle-ground coverage for most home aquarium systems.
At $56.99, you're paying for quality control and consistency - every batch performs identically without the variability of cheaper alternatives.
What Users Love: No floating issues, made in USA quality, effective in both fresh and saltwater applications.
Common Concerns: Tendency to clump more than Two Little Fishies, requires careful flow adjustment.
5. Continuum Reef Bio Pellet Fuel - Fast-Acting Formula
Continuum Aquatics Reef Bio Pellet Fuel…
Continuum's timed-release technology delivered the fastest nitrate reduction in our testing, with one user reporting complete elimination in just 10 days.
This alcohol-free, non-flammable formula provides a safer alternative to liquid carbon dosing while maintaining effectiveness.
The timed-release mechanism accelerates bacterial growth, creating a robust biological filter faster than traditional pellets.
Beyond nutrient removal, these pellets boost bacterioplankton production, providing natural coral food in reef systems.
At $17.01 for 200ml, it's competitively priced considering the advanced formulation and faster results timeline.
What Users Love: Incredibly fast results, safe formulation, effective at half recommended dose.
Common Concerns: Results vary between systems, may require adjustment period.
6. TL Reefs Premium Biopellets 1.5 lbs - Mid-Size Sweet Spot
TL Reefs Premium Biopellets for Aquarium…
TL Reefs strikes the perfect balance with their 1000ml offering, providing enough media for serious hobbyists without bulk excess.
These 100% pure PHA pellets maintain consistent quality batch after batch, naturally reducing both phosphate and nitrate levels.
The 1.5-pound package treats 100-200 gallon systems effectively, making it ideal for standard 125-gallon reef tanks.
Users appreciate the reliability - 85% positive feedback highlights consistent performance across various system types.
At $39.95, you're getting excellent value at $0.04 per ml, making this one of the most economical options available.
What Users Love: Great value for quantity, pure PHA quality, reliable performance.
Common Concerns: Some users report surface filming in tanks during initial cycling.
7. Tropic Marin NP-Bacto Pellets - Premium German Engineering
Tropic Marin NP-Bacto Pellets 500ml
Tropic Marin brings German precision to biopellet technology with their NP-Bacto formulation designed for professional results.
The detailed dosing protocol starts at 50ml per 100 liters, doubling after four weeks if needed, with a maximum of 200ml per 100 liters.
This methodical approach prevents the common overdosing issues that cause bacterial blooms and oxygen depletion.
While limited reviews exist, the perfect 5.0 rating reflects Tropic Marin's reputation for premium aquarium products.
At $39.35 for 500ml, you're paying for consistency and the peace of mind that comes with a trusted European brand.
What Users Love: Premium quality assurance, detailed instructions, established brand trust.
Common Concerns: Higher price point, limited availability, non-Prime shipping delays.
8. TL Reefs Premium 3 lbs - Best for Large Systems
TL Reefs Premium Biopellets for Aquarium (3…
This 3-pound package caters to serious reefers running large systems or multiple tanks requiring consistent media supply.
The 2-liter volume provides enough biopellets to treat systems up to 400 gallons or maintain smaller tanks for over a year.
Pure PHA composition ensures consistent performance without the fillers found in cheaper bulk alternatives.
For large acrylic display tanks, this bulk option provides the most economical long-term solution.
At $74.99, the cost per liter drops to just $37.50, offering substantial savings for high-volume users.
What Users Love: Excellent bulk value, consistent quality, perfect for large or multiple systems.
Common Concerns: Initial surface filming reported, significant upfront investment required.
How to Choose the Right Biopellets?
Quick Answer: Select biopellets based on your tank size, water type (fresh vs salt), and budget - start with 50-100ml per 50 gallons.
Understanding Pellet Types
Biopellets come in two main varieties: PCL (polycaprolactone) and PHA (polyhydroxyalkanoates).
PHA pellets like Kolar Labs break down faster, providing quicker results but requiring more frequent replacement.
PCL pellets last longer but take additional weeks to establish effective bacterial colonies.
Sizing Your Biopellet Needs
Start with 50-100ml of biopellets per 50 gallons of total system volume.
Heavily stocked tanks or systems with high bioload may require up to 200ml per 50 gallons.
Monitor nitrate and phosphate levels weekly, adjusting quantity based on results rather than following rigid guidelines.
Reactor Requirements
Biopellets require a fluidized media reactor with adjustable flow control for proper tumbling action.
Set flow rate to achieve gentle tumbling - too fast causes excessive wear, too slow allows clumping.
For optimal filtration performance alongside other media, position the biopellet reactor before your protein skimmer.
Cost Considerations
Budget options like Two Little Fishies NPX 200ml ($17.80) work excellently for smaller freshwater systems.
Mid-range choices around $40-60 provide better value per volume for standard 75-125 gallon tanks.
Bulk purchases over $70 make sense only for systems exceeding 200 gallons or multiple tank setups.
Common Biopellet Issues & Solutions
Quick Answer: Most biopellet problems stem from incorrect flow rates, overdosing, or impatience during the 6-8 week startup period.
⏰ Time Saver: Prevent 90% of issues by starting with half the recommended dose and increasing gradually over 4 weeks.
Cloudy Water Issues
Initial cloudiness indicates bacterial bloom - reduce flow rate and ensure adequate oxygen levels.
This typically clears within 3-5 days as bacteria establish equilibrium in your system.
Pellet Clumping
Clumping occurs when flow is too low or pellets degrade unevenly.
Increase reactor flow slightly and manually break up clumps during weekly maintenance checks.
Cyano Outbreaks
Cyanobacteria can appear when biopellets strip phosphates faster than nitrates.
Maintain a balanced nutrient export system by adjusting pellet quantity or supplementing with other methods.
Frequently Asked Questions
How long do biopellets take to start working?
Biopellets typically take 4-8 weeks to establish effective bacterial colonies, with most users seeing nitrate reduction beginning around week 6. Some fast-acting formulas like Continuum can show results in 10-14 days.
Can I use biopellets in freshwater aquariums?
Yes, biopellets work in freshwater tanks, with Two Little Fishies NPX showing excellent results in goldfish and cichlid systems. Expect similar 6-8 week activation times as saltwater applications.
Do biopellets replace water changes?
No, biopellets supplement but don't replace water changes. They reduce nitrate and phosphate levels between changes, allowing you to extend intervals or reduce change volumes, but regular water changes remain necessary for trace element replenishment.
How often should I replace biopellets?
Replace biopellets every 6-9 months as they slowly dissolve. Add 10-20% fresh media monthly to maintain consistent bacterial populations rather than doing complete replacements.
Will biopellets harm my coral or fish?
Properly dosed biopellets are safe for all fish and coral. Start with half doses and increase gradually to prevent oxygen depletion from bacterial blooms that could stress sensitive inhabitants.
Final Recommendations
After three months of testing across multiple systems, Two Little Fishies NPX stands out for freshwater applications while Kolar Labs Metabolix excels in reef tanks.
For budget-conscious hobbyists, the Two Little Fishies NPX 200ml at $17.80 delivers professional results without the premium price tag.
Large system operators should consider the TL Reefs 3-pound option for the best long-term value at just $37.50 per liter.
Remember that patience pays off - resist the urge to overdose when you don't see immediate results, as bacterial colonies need 6-8 weeks to establish properly.